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5 articles · antioxidants
LetsGo Care Editorial
High-dose antioxidant pills keep failing the more-is-better test: what to ask before you pay
High-dose isolated antioxidant capsules repeatedly show null or harmful outcomes in randomized trials, whereas food-derived polyphenols upregulate endogenous defense pathways like Nrf2 without blunting beneficial…
LetsGo Care Editorial
Why do whole-food antioxidants outperform high-dose antioxidant supplements?
Large randomized controlled trials show that high-dose isolated antioxidant pills do not prevent chronic disease and can increase mortality, while dietary polyphenols and carotenoids activate the Nrf2 pathway and lower…
LetsGo Care Editorial
High-dose antioxidant pills keep failing the more-is-better test: what a household can actually keep
Large randomized controlled trials show that high-dose isolated antioxidant pills like beta-carotene and vitamin E fail to prevent chronic disease and can increase all-cause mortality, whereas food-based polyphenols…
LetsGo Care Editorial
High-dose antioxidant pills keep failing the more-is-better test: the claim versus the human data
Large randomized controlled trials show that high-dose isolated antioxidant pills either fail to reduce cardiovascular and cancer mortality or actively increase risk, whereas food-based polyphenols stimulate endogenous…
LetsGo Care Editorial
Do high-dose antioxidant supplements work as well as food-first diets?
Large randomized trials of isolated high-dose antioxidant pills repeatedly show null or harmful effects on mortality, whereas food-first polyphenols and carotenoids work by activating the endogenous Nrf2 cellular…